Bibliography of Studies About HL7® FHIR®

App SJ, Meyer AM, Silkensen S, Hudson C, Inman I, Niedner RH, Sincan M, Shaalan Beg M, Topaloglu U. Follow the data: tracking data quality and completeness in oncology real-world data. JAMIA Open. 2026 June;9(3):ooag052. PMCID: PMC13143418 Cite

Wi CI, Overgaard S, Malik M, Watson D, Sharma D, Le-Rademacher J, Kelleher D, Zheng L, Ohde J, Lynch B, Khurana A, Sohn S, AlJuhani MM, Carpenter C, Arteta M, Greenwood J, Hartz M, Foss R, Polat E, Absah I, Davis C, Gupta M, Myers L, Nordlund B, Tao C, Wieland ML, Patten C, Jones A, Varkey P, Loufek BT, Vidal DE, Gopala N, Klee E, Shah VH, Halamka JD, Callstrom MR, Rider NL, Liu H, Aliferis C, D Garovic V, J Juhn Y. A lifecycle governance and learning health system framework for trustworthy, generalizable, and sustainable human-ai partnership in clinical practice: Lessons from the asthma-guidance and prediction system (A-GPS). J Natl Med Assoc. 2026 May 13;S0027-9684(26)00064–7. PMID: 42128801 Cite

Park K. Diagnostic stewardship monitoring systems: institutional and system-level approaches. Crit Rev Clin Lab Sci. 2026 May 12;1–17. PMID: 42116750 Cite

Bikia V, Schmiedmayer P, Zahedivash A, Aalami L, Rao A, Ravi V, Turk M, Ceresnak SR, Aalami O. Spezi Data Pipeline: Streamlining FHIR-based interoperable digital dealth data workflows. NPJ Digit Med. 2026 May 12; PMID: 42120671 Cite

Ungurean I, Gherman OI, Lavric A, Dimian M. A privacy-centric microservice framework for secure FHIR-based integration of heterogeneous medical data. Int J Med Inform. 2026 May 11;216:106477. PMID: 42114371 Cite

Strate J, Hering A, Brintrup R, Krefting D, Hübner UH. Assessing the Compliance of Nursing Data in a Rehabilitation Portal with the German ePatient Record (ePA) Standard for Nursing Discharges. Stud Health Technol Inform. 2026 May 7;335:7–13. PMID: 42119083 Cite

Helm E, Schuler A, Leonhartsberger G, Riva G, Dietrich R, Scholz B, Buchmann M, Sabutsch S. Towards the Austrian Patient Summary: Implementation Strategy and Architecture. Stud Health Technol Inform. 2026 May 7;335:22–27. PMID: 42119085 Cite

Staemmler M, Freier N, Klimm F, de Haas G. Health Harbor Hamburg (H3): A Federated Health Data Space. Stud Health Technol Inform. 2026 May 7;335:82–88. PMID: 42119096 Cite

Hochwarter S, Ban M, Dorner TE, Haider S, Jeleff M, Lichtenegger K, Weitlaner T, Feichtner F. From Guidelines to Action: A Systematic Approach to Translating Health Indicators into a Digital Prevention Ecosystem. Stud Health Technol Inform. 2026 May 7;335:129–130. PMID: 42119104 Cite

Schlosser J, Kastner P, Vinatzer H, Ziegl A, Steiner K, Schreier G. A Fit-Gap Analysis of Care Planning Tools: Evaluating FHIR Compliance. Stud Health Technol Inform. 2026 May 7;335:163–168. PMID: 42119113 Cite

Krauss O, Pointner A, Praschl C. Managing Incompatible FHIR Implementation Guides in a Single Backend: Namespace-Based Storage in Neo4j and Multi-Profile Delivery. Stud Health Technol Inform. 2026 May 7;335:203–209. PMID: 42119121 Cite

Bruthans J, Hospodková P, Fejfarová I. Stakeholder Perspectives on Affinity Domains in Digital Health Interoperability: Qualitative Study. JMIR Med Inform. 2026 Apr 2;14:e83894. PMCID: PMC13046094 Cite

Kirchsteiger K, Heiler L, Bödenler M, Hanke S. Integrating Medication Leaflets Utilizing FHIR and an LLM-Based Question-Answer Pipeline in a Mobile Application. J Med Syst. 2026 Apr 1;50(1):43. PMCID: PMC13038807 Cite

Turki AT, Brieske CM, Gurkan UA, Scheidler KM, Usta OB, Turkulainen E, Arzideh K, Temme C, Hosch R, Horn PA, Arvas M. Fundamentals of big data and artificial intelligence in transfusion medicine. Vox Sang. 2026 Apr;121(4):430–440. PMCID: PMC13066920 Cite

Plass M, Holzinger A, Reihs R, Müller H. Integrating AI into clinical practice: Human-centered design requirements for next-generation sequencing workflows. Comput Med Imaging Graph. 2026 Apr;130:102758. PMID: 41921369 Cite

Dolin RH, Heale BSE, Patterson J, Power KM, Terry M, Anton H, Chen J, Sawant K, Chamala S. Assessment of the adequacy of the Fast Healthcare Interoperability Resources (FHIR) Genomics standard for the representation of somatic testing reports. JAMIA Open. 2026 Apr;9(2):ooag022. PMCID: PMC12963594 Cite

Chauhan C, Parwani A, Schumacher V, Sebastian M, Bui MM, Lin PC, Blakely S, Fathima S, Gibbs J, Horchner U, Lujan G, Osamura RY, Pantanowitz L, Samboy J, Zioga C, Herrmann M, Yeh J, Oen H, Dash RC, Lennerz JK, Schmid J. The critical role of standards for AI in digital pathology: Digital Pathology Association Concept Paper. J Pathol Inform. 2026 Apr;21:100645. PMCID: PMC12969082 Cite

Phuyal S, Bhandari M, Bista R, Ferreira JC. HL7 FHIR consent for healthcare data sharing: challenges, opportunities and integrity implications. Int J Med Inform. 2026 Mar 27;214:106405. PMID: 41905015 Cite

Marfoglia A, Arcobelli VA, Moscato S, La Mattina AA, Mellone S, Carbonaro A. Challenges of health data standard adoption and usage: a systematic review. J Biomed Inform. 2026 Mar 21;178:105022. PMID: 41871756 Cite

Isaradech N, Sirikul W, Schulz S, Kreuzthaler M. Ontology-Based Medication Named Entity Recognition Using Pretrained Transformer Models From a Thai Hospital: Model Fine-Tuning and Validation Study. JMIR Form Res. 2026 Mar 20;10:e82685. PMCID: PMC13004563 Cite

Kämmerer M. [Possibilities for integrating artificial intelligence into the diagnostic process]. Radiologie (Heidelb). Heidelberg, Germany; 2026 Mar 18; PMID: 41848781 Cite

Tcheng JE, Finney D, Boone K, Desai SP, Pyke DA, Shanbhag N, Srinivasan G, Ramsing N, Kelemen MD. Evaluating the potential of fast healthcare interoperability resources for clinical registry data submission. J Am Med Inform Assoc. 2026 Mar 9;ocag029. PMID: 41801964 Cite

Naliyatthaliyazchayil P, Stenerson T. Harmonizing Logical Observation Identifiers Names and Codes (LOINC) Codes and Units in Real-World Oncology Data: Method Development and Evaluation. JMIR Med Inform. 2026 Mar 9;14:e81254. PMID: 41802234 Cite

Schmiedmayer P, Johnson A, Schuetz N, Kollmer L, Goldschmidt P, Delgado-SanMartin J, Zhang KW, Mantena S, Tolas A, Montalvo S, Ramirez-Posada M, O’Sullivan JW, Oppezzo M, King AC, Rodriguez F, Ashley E, Lawrie A, Kim DS. Design and Rationale of the My Heart Counts Cardiovascular Health Study: a Large-Scale, Fully Digital Biobank, and Randomized Trial of Large Language Model-Driven Coaching of Physical Activity. medRxiv. 2026 Mar 3;2026.03.02.26347447. PMCID: PMC13001391 Cite

Tamana S, Yiangou K, Orphanou K, Chatzimatthaiou S, Kountouris P, Cremonesi F. FAIR data gaps and collaboration willingness among hemoglobinopathy research centers. Sci Data. 2026 Mar 3; PMID: 41775724 Cite

Cahill M, O’Shaughnessy F, Boland F, Ainle FN, Donnelly J, Cullinan S, Cleary BJ. Accuracy, Efficiency, and usability of a Semi-Automated SMART on FHIR venous thromboembolism risk assessment App: A randomised crossover simulation study. Int J Med Inform. 2026 Mar 3;213:106367. PMID: 41785738 Cite

Tahar K, Verbuecheln R, Martin T, Graessner H, Biergans S, Krefting D. Sharing EHR data of patients with rare diseases for research - The role of quality assessments in a national federated research data infrastructure. BMC Med Inform Decis Mak. 2026 Mar 2;26(1):60. PMCID: PMC12955070 Cite

Kubota K, Urakawa R. From “Black Box” to Learning System: Formative Viewpoint on Digital Health Governance for Childhood Cancer Information in Japan. JMIR Form Res. 2026 Feb 25;10:e86775. PMID: 41740961 Cite

Norouzi S, Agah J, Sarkohi Z, Ahmadian L. Development of a minimum data set for a pediatric and neonatal Medication Administration Clinical Decision Support System (MACDSS), mapped to FHIR: a mixed-methods research synthesis. BMC Med Inform Decis Mak. 2026 Feb 21; PMID: 41723409 Cite

Ehrler F, Rajic A, De Masi A, Olanka S, Generelli M, Davidson J, Lin Y, Kim K, Rebours PL, Ibrahim M, Duncan D, Kang R, Manzano S, Cheng A, Siebert JN. Overview of a User-Centered, Mixed-Methods Process for Designing Interconnected and Focused Mobile Applications on Patient Care Environment (InterFACE): Augmented-Reality Decision Support System for Pediatric Resuscitation. JMIR Hum Factors. 2026 Feb 13;13:e78144. PMCID: PMC12904346 Cite

Ilamvaluthy Y, Nadeswaran T. Enabling Data Sharing for Hospital-to-Community Transitions in the Toronto Region: A Stakeholder-Informed System Architecture Solution. Stud Health Technol Inform. 2026 Feb 12;334:57–61. PMID: 41685473 Cite

Numor S, Keshavjee K, Vitorelli R. Designing a Trace-Monitor-and-Act Surveillance Framework for Preventing Foodborne Disease Outbreaks in Ghana. Stud Health Technol Inform. 2026 Feb 12;334:148–149. PMID: 41685498 Cite

Alper BS, Dehnbostel J, Lehmann H. Evidence-based medicine on FHIR augments the standards-based approach to digital health research. J Am Med Inform Assoc. 2026 Feb 10;ocag024. PMID: 41691655 Cite

Mokssit Y, Ravi K, Nie M, Kim J, Liu C. FHIR-AgentEval: A Modular Sandbox for Benchmarking Clinical LLM Agents with an Evaluation of Memory-Augmented Configurations. Res Sq. 2026 Feb 9;rs.3.rs-8746188. PMCID: PMC12919212 Cite

Hoang MT, Donnelly C, Igasto C, Shetty A, Pradhan M, Shaw T. Data-Driven Guideline Adherence in Data Representation and Compliance Measurement: Scoping Review. J Med Internet Res. 2026 Feb 9;28:e79937. PMCID: PMC12885449 Cite

Hamamoto R, Koyama T, Takahashi S, Yasuda T, Kobayashi K, Akagi Y, Kouno N, Sudo K, Hirata M, Sunami K, Kubo T, Katayama H, Takashima A, Taniguchi T, Matsumoto H, Shibaki R, Asada K, Komatsu M, Kaneko S, Yamada M, Horinouchi H, Tanaka K, Goto Y, Kato K, Saito Y, Nakamura K, Yamamoto N. Implementing generative artificial intelligence in precision oncology: safety, governance, and significance. J Hematol Oncol. 2026 Feb 9;19(1):14. PMCID: PMC12896320 Cite

Marsolo K, Louzao D, Hart K, Shrader P, Hawley J, Delacqua F, Thomas E, Wick J, Chamberlain AM, Jones WS, Rothman R, Harris PA, Cheng AC. Investigating the Use of the Fast Health Care Interoperability Resources (FHIR) Standard to Support Data Activities Across the PCORnet® Infrastructure: Lessons Learned From the FHIR Pilots of the Coordinating Center for PCORnet®. Med Care. 2026 Feb 1;64(2S Suppl 3):S233–S241. PMCID: PMC12783352 Cite

Kramer MA, Mathur A, Adams CE, Walonoski JA. Leveraging generative AI to enhance Synthea model development. JAMIA Open. 2026 Feb;9(1):ooaf123. PMCID: PMC12772637 Cite

Mazumder R, Keeney J, Johnson L, Krammer L, McNeely P, Sepulveda J, Hangen D, Martin M, Jyothi D, De Almeida J, McGarvey P, Alaoui A, Cha S, Sedrakyan A, Shoelle E, Matheny M, LeNoue-Newton M, Winter R, Deppen S, Simonyan V, Horvath A. From use cases to infrastructure: a cross-institutional survey of priorities in data-driven biomedical research. J Am Med Inform Assoc. 2026 Jan 20;ocag001. PMID: 41556955 Cite

Tremper G, Brenner T, Ben Amor M, Kussel T, Lablans M. Mainzelliste: Ten years of pseudonymization, record linkage, and informed consent management. Patterns (N Y). New York, N.Y.; 2026 Jan 9;7(1):101432. PMCID: PMC12827741 Cite

Kim B, Lee J. Development of a FHIR-based Korean IPS Data Pipeline and User-Centered UI Design. Sci Rep. 2026 Jan 6; PMID: 41495243 Cite

Ohlsen T, Sander A, Ingenerf J. ECLed- a tool supporting the effective use of the SNOMED CT Expression Constraint Language. J Biomed Semantics. 2026 Jan 6;17(1):1. PMCID: PMC12777381 Cite

Garza MY, Wang Z, Adagarla B, Rutherford MW, Topaloglu U, Benjamin DK, Zimmerman KO, Eisenstein EL, Kumar KR, Best Pharmaceuticals for Children Act – Pediatric Trials Network Steering Committee. Evaluation of electronic health record to HL7® FHIR® mappings in pediatric research studies. Int J Med Inform. 2026 Jan 4;209:106265. PMID: 41529640 Cite

Traverso A, Tiano D, Corvaglia A, Dimonte A, Draetta EL, Fabiani B, Scuri P, Barbieri S, Agazzi M, Arslan M, Celada D, Chiabrando F, Cibrario L, Cielo G, Colombo A, Contini S, Liberotti M, Montagna M, Ogliari FR, Palmisano A, Pisu F, Serra D, Varani D, Vignale D, Vitali AL, Zambello A, Chiapponi C, Denti M, Esposito A, Tacchetti C. Powering responsible artificial intelligence with high-quality real-world data: the S-RACE platform for scalable, multi-specialty clinical research. NPJ Digit Med. 2026 Jan 3;9(1):6. PMCID: PMC12770359 Cite

Sunchu K, Desai AP, Vuppalanchi R, Purkayastha S. A pilot feasibility study of human-centered design for cirrhosis care: Development and pilot testing of SMARTLiver prototype, a FHIR-based clinical decision support system for hepatology. PLOS Digit Health. 2026 Jan;5(1):e0000969. PMCID: PMC12818595 Cite

LeGrand J, Ali MS, Flynn A, Arzac J, Lester C, Dorsch MP. Linking FHIR-Based Medication Data to a Computable Algorithm for Heart Medication Optimization: A Critical Component of Any Medication Learning Health System. Learn Health Syst. 2026 Jan;10(1):e70064. PMCID: PMC12816155 Cite

Nopour R. Using FHIR for data sharing: A scoping review of challenges and facilitators in healthcare settings. Int J Med Inform. 2026 Jan;205:106128. PMID: 41072202 Cite

Papaioannou M, Neocleous A, Savva P, Yiasemi C, Michael C, Canciu IC, Constantinou I, Adamides G, García Miguel F, Panayides A, Antoniou Z, Schiza E, Panos GZ, Samoutis G, Pattichis CS, Schizas CN. eHealth4U: A pathway from the Cyprus eHealth law to a citizen-centred national EHR prototype interoperable with myHealth@EU and international patient summary. Digit Health. 2026;12:20552076261431813. PMCID: PMC13133457 Cite

Nieminen L, Anttila H, Ketamo H, Zampolini M, Martinuzzi A, Della Mea V. A call for action to strengthen stakeholder readiness for ICF data exchange in European health data space: a structured narrative review. Front Public Health. 2026;14:1786004. PMCID: PMC13136167 Cite

Al-Ganad A, Al-Shahdhi A, Al-Dhaifi O, Hajeb E, Hajeb H, Al-Motarreb A. Deploying medical AI in low-resource settings: a scoping review of challenges and strategies. Front Digit Health. 2026;8:1743634. PMCID: PMC13096741 Cite